Opembedza omwe adalowa m'malo opanda anthu kumpoto kwa New Spain anali ndi lingaliro lotembenuza mayiko "achilendo" kukhala Chikhristu ndipo nawonso amawaphatikiza mu moyo wandale, kuti pambuyo pake apeze masukulu ndi mizinda m'midzi yomwe idakhazikitsidwa kale.
Kuti akwaniritse izi, makolowo, omwe nthawi zonse amakhala ndi magulu ankhondo, amapita kwa Amitundu ndikuwapatsa chitetezo ku Tchalitchi ndi Korona waku Spain posinthana ndi maphunziro achikhristu. Amwenye omwe adalandira, adasonkhana kuti apange ntchito, ndikukhala malo othawirako Amwenye komanso malo ophunzirira maluso aku Europe aulimi ndi ntchito zina.
Kukhazikika kukamalizidwa, mishoni idakhala tawuni yaying'ono yokhala ndi tchalitchi, pomwe amishonalewo adasamukira kwina kuti akayambitsenso ntchito yawo yolalikira. Njirayi inali yowopsa, chifukwa amwenye akumpoto adalimbana nawo, chifukwa anali amwano kuposa omwe anali pakatikati, ndipo adathawira kumapiri.
Kutembenuka kunagwira ntchito potengera mphotho ya malo ndi chitetezo kwa amwenye posinthana ndi kumvera. Omwe adatsutsa adalangidwa, pomwe omwe adapanga zigawenga amaphedwa.
Mtundu wakomweko utasonkhanitsidwa, gawo lalikulu kapena mutu udaphatikizidwa, womwe umapangidwa ndi matauni angapo ndi midzi yomwe inali pansi pake. Amishonalewa ankakhala kunyanja ndipo ankayang'anira midzi iwiri. Amishonale atatu kapena kupitilira apo adadalira woyang'anira komanso mlendo wamba. Malo awa pamodzi adapanga Chigawo.
Choyamba, tchalitchi chopangidwa ndi miyala chinamangidwa ndipo mozungulira icho, ndi adobe, nyumba zidamangidwa kwa ma friars omwe amapita kukalalikira, dzuwa, dayisi komanso mabanja achikhalidwe, komanso sukulu. M'mabungwewa panali zomwe titha kuzitcha dongosolo lazachuma. Iwo anali ndi malo olimapo, kufesa nthaka, kutsegula misewu ndi ngalande zothirira; kuweta ziweto, masamba ndi ntchito zaluso. Katekisimu, kuwerenga, kulemba ndi nyimbo amaphunzitsidwa m'sukulu.
Pakapita nthawi, ntchito zina zidasiyidwa kwathunthu chifukwa cha zochitika zosiyanasiyana, monga kuthamangitsidwa kwa Ajezwiti mu 1767, kufalikira kwa matenda obwera ndi aku Spain, kuwukira kwa Amwenye "achilendo", nyengo, nyengo yayitali ndi ndalama zochepa zowasamalira. Ena amasungidwa lero ngati mipingo ndipo ena tsopano ndi anthu ofunikira kwambiri. Komabe, mwa mautumiki ena malo okha omwe adakhalapo poyamba amadziwika ndi ena mwa mabwinja okha omwe atsala.
AJesuit adakhazikitsa mishoni ku Baja California Norte ndi Sur, Sonora, Sinaloa, Chihuahua, kumpoto kwa Nayarit, mbali ya Durango ndi Coahuila. Atachoka, a Dominican adakhazikika kumpoto kwa Baja California, pomwe Afranciscans amalalikira Tamaulipas ndi Nuevo León ndikusintha amishonale a Order of Loyola kumwera chakumwera kwa Baja California, Sonora, Sinaloa, Chihuahua, Nayarit, Durango ndi Coahuila. Kumpoto chapakati, pambuyo pa kupanduka kwa a Zacateco —omwe adalepheretsa amisili aku Franciscan kupitiliza -, mbadwa zawo zidadzikonzekeretsa m'misasa.
Mu 1563 Captain Francisco de Ibarra adayendera madera omwe akuphatikizanso dziko la Sinaloa ndikukhazikitsa matauni ena. Komabe, izi zidatenga kanthawi kochepa ndipo sizinafike mpaka 1591 pomwe malinga ndi kazembe wa Nueva Vizcaya, abambo achi Jesuit a Gonzalo de Tapia ndi a Martín Pérez adapatsidwa ntchito yolalikira m'derali.
Opembedzawo adadutsa ku Sierra Madre Occidental mu Meyi chaka chomwecho, ndikudutsa ku Acaponeta, Nayarit, ndikudutsa ku Culiacán adafika pamalopo, pomwe pa June 6, 1591 adakhazikitsa nyumba yawo yoyamba: San Felipe de Sinaloa.
