Zotsalira zakale za Ixtépete, malo azikumbutso pafupi ndi mzinda wa Guadalajara mumzinda wa Zapopan ndi zomwe zapezedwa posachedwa pamanda opitilira makumi awiri mchigwamo ku Atemajac Valley, zimatilola kunena kuti panali ntchito zofunikira munthawi yachikale (200 BC-650 AD)
Atatsala pang'ono kugonjetsa, m'chigwachi munkakhala anthu ambiri ndi magulu a Cocas ndi Tecuexes, omwe amasonkhana m'midzi yaying'ono yodalira ulamuliro wa Tonallan, yomwe idaperekedwa popanda kukana kwa Nuño Beltrán de Guzmán mu 1530.
Kumapeto kwa chaka chotsatira, Guzmán adagonjetsa kumpoto, ndikupatsa Juan de Oñate kuti awoloke chigwa cha Santiago ndipo momwe angathere koma mwanzeru, adapeza anthu aku Spain osadziulula. Chifukwa chake, pa Januware 5, 1532, pafupi ndi Nochistlán, ku Zacatecas masiku ano, Guadalajara idakhazikitsidwa.
Zinthu zomwe zidasowetsa mtendere anthuwo zidapangitsa kuti mzindawu usamutsiridwe kupita ku Tonalá, koma kukhalako komweko sikunakhalitse ndipo patangopita nthawi pang'ono anthu aku Spain adakhazikika pafupi ndi Tlacotan, komwe adakhalako mpaka 1541. Kupanduka kwa a Caxcanes omwe amadziwika kuti nkhondo ya Mixtón, yomwe adaika pachiwopsezo chachikulu ulamuliro waku Spain, udafika mpaka madera ozungulira Guadalajara. Ndi kupanduka komwe "pansi pamoto ndi mwazi" ndi gulu lamphamvu lankhondo lotsogozedwa ndi Viceroy Antonio de Mendoza, mzindawu udafika pamtendere koma adasiyidwa opanda anthu wamba, chifukwa chake, powasaka, adaganiza zosuntha anthu, ndikupeza okwanira Valle de Atemajac, pomwe maziko omaliza komanso omveka adapangidwa pa February 14, 1542. Pambuyo pake, nkhaniyi idatsimikizika kuti, pafupifupi zaka zitatu izi zisanachitike, mfumu idalipatsa udindo komanso mwayi wamzindawu.
Mu 1546 Papa Paul III adapanga Bishopu ya Nueva Galicia ndipo mu 1548 Audiencia ya dzina lomweli idakhazikitsidwa; Likulu la madera onsewa, ku Compostela, Tepic, mpaka mu 1560 lidasinthidwa kusintha kwa Guadalajara, ndikupangitsa kuti akhale mtsogoleri woweruza m'chigawo chachikulu chotchedwa Audiencia cha Guadalajara, likulu la Kingdom of Nueva Galicia ndi mpando wa Bishopu. Pomwe mzinda uliwonse waku Spain udapangidwa ngati chessboard kuchokera kudera lalikulu la San Fernando komanso monga mwamwambo, madera akomweko a Mexicaltzingo, Analco ndi Mezquitán adasiyidwa. Ntchito yolalikira idayambitsidwa ndi Afranciscans, ndikutsatiridwa ndi A Augustinians ndi maJesuit.
Pang'ono ndi pang'ono, pamavuto ndi zovuta zina komanso zopambana, Guadalajara idakula ndikudziyambitsa yokha ngati likulu lazachuma komanso mphamvu, kotero kuti pakati pa zaka za zana la 18 anthu ambiri olemera ochokera ku Guadalajara amafuna Nueva Galicia ndi Nueva Vizcaya kuti aphatikize kudziko lachilendo kwathunthu. kupita ku New Spain, cholinga chomwe sichinakwaniritsidwe chifukwa kusintha kwa kayendetsedwe ka ndale mu 1786 kunali pakhomo, komwe kunasintha madera, kugawa kukhulupirika konse m'matauni 12, umodzi mwa iwo unali Guadalajara.
Munthawi yamakoloni, makamaka m'zaka za zana la 18, kuchuluka kwachuma kudasiya cholowa chamapangidwe, zikhalidwe komanso zaluso, maumboni omwe adakalipobe mzindawo.
Maulendo olimbikitsa ufulu wodziyimira pawokha omwe amayenda kudera lonse la New Spain adalowa mu Jalisco, kotero kuti nkhondo yodziyimira payokha itayamba m'mbali zosiyanasiyana za Municipal munali zipolowe.
Pa Novembala 26, 1810, a Don Miguel Hidalgo, olamula gulu lankhondo lalikulu, adalowa ku Guadalajara ndipo adalandiridwa ndi a José Antonio Torres, omwe anali atangotenga kumene mzindawu. Hidalgo pano adapereka lamulo lothetsa ukapolo, mapepala osindikizidwa ndi alcabalas ndikuthandizira kusindikiza nyuzipepala ya zigawenga El Despertador Americano.
Pa Januware 17, 1811, zigawengazo zidagonjetsedwa pa mlatho wa Calderón ndipo asitikali achifumu ku Calleja adalandiranso Guadalajara, poganiza kuti lamuloli José de la Cruz, yemwe ndi Bishop Cabañas, adathetsa kuwukira kulikonse.
Adalengeza ufulu wawo mu 1821, boma laulere komanso lodziyimira palokha la Jalisco lidakhazikitsidwa, kusiya Guadalajara likulu la boma komanso mpando wa maulamuliro.
Kusakhazikika komwe kudachitika mzaka za zana la khumi ndi chisanu ndi chinayi mdzikolo, zomwe zidakulitsidwa ndi kuwukira kwakunja, zidapangitsa kuti zikhale zovuta, koma sizinalepheretse boma makamaka likulu lake kupitiliza chitukuko m'njira zosiyanasiyana. Zitsanzo zowoneka ndi izi: m'gawo lachiwiri lazaka, kukhazikitsidwa kwa Institute of State Sciences; ntchito yomanga School of Arts and Crafts, Botanical Garden, Pritentiary and the Pantheon of Bethlehem, komanso kutsegula kwa mafakitale oyamba.
Kumayambiriro kwa zaka makumi asanu ndi atatu, kutulutsa nyama m'matauni kunawonekera, magetsi adakhazikitsidwa mu 1884, mu 1888 njanji yoyamba ku Mexico idafika ndi ya Manzanillo mu 1909. M'zaka za m'ma 90, Don Mariano Bárcena adayambitsa Astronomical Observatory ndi Museum Museum.
Panthawiyi, ku Guadalajara panali zinthu zina zopandukira olamulira mwankhanza a Díaz, monga kunyanyala kwa ogwira ntchito komanso ziwonetsero za ophunzira, ndipo Madero adalandiridwanso mu 1909 ndi 1910 ndi mawu achifundo. Komabe, panalibe zachiwawa zomwe zidachitika pambuyo pake. Kumbali inayi, likulu la Guadalajara lidakumana ndi mavuto omwe adatha mu 1930 pomwe mtendere womwe udasokonekera ndi nkhondo ya Cristeros udavomerezedwa, ndikuyamba kufunafuna kwamakono komwe sikunathe.
Onaninso Mizinda Yachikoloni: Guadalajara, Jalisco
